Dr. Kyle C. Smith, PhD

Kyle C. Smith, PhD

R&D Executive | Technology Commercialization

Driving novel technology platforms from concept to commercial launch in the MedTech and Life Science industries.


Core Competencies

• R&D Strategy• Team Leadership• Fundraising
• IP Strategy• Platform De-risking• Strategic Partnerships

Career Highlights

  • Led two startups from founding to commercial launch

  • Secured $38M+ in milestone-based funding

  • Anchored a $35M+ strategic R&D partnership with J&J

  • Invented foundational IP licensed by multiple spinout companies


I build the bridge between breakthrough science and commercial reality. For over a decade, I've focused on translating complex technology from the lab into valuable, market-ready products – a playbook I've honed as a founding team member of two deep-tech ventures.My leadership is defined by pragmatic execution and strategic resilience. At MicroMedicine, I architected the R&D engine that secured $38M in funding milestones and launched its first commercial platform. More recently, as Co-Founder and CTO of BendBio, I engineered a critical pivot to a capital-efficient model that achieved profitability while preserving 100% of founder equity.My philosophy is that R&D should be predictive, not reactive. Grounded in a first-principles approach honed at MIT and MGH, I de-risk technology early and build capital-efficient roadmaps by applying systematic analysis and model-informed insights. This approach provides the technical clarity and strategic confidence that leadership, boards, and investors need to move forward.Having successfully guided these ventures, I am now seeking my next senior leadership challenge as a CTO, VP R&D, or Operating Partner. I am focused on applying this playbook to scale the next generation of transformative therapeutic and diagnostic platforms.

© 2025 Kyle C. Smith | Cambridge, MA | All Rights Reserved